Abstract. DExH/D proteins are essential for all aspects of cellular RNA metabolism and processing, in the replication of many viruses and in DNA replication.

An alternative model that invokes fundamental mechanistic differences among various DExH/D box proteins could entail direct binding of the DExH/D box NTPase to ...

Here we review recent studies that highlight physiological roles of DExH/D proteins in the displacement of proteins from RNA. We further discuss work with ...

DHX9 (also known as RNA helicase A) is a multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and plays ...

2023/03/16 · A bioinformatic analysis reveals that this RNA-driven ATPase activation is conserved only across the DExH-box RNA helicases which, besides ...

The DHX RNA helicases family includes a large number of proteins that are implicated in RNA metabolism. Members of this family, RIG-1 and MDA5, have been shown ...

We report the 2.9-Å resolution crystal structure of Saccharomyces cerevisiae Mtr4 in complex with ADP and RNA. The structure shows a central ATPase core similar ...

2023/12/07 · In brief. Jagtap et al., combining structural and functional studies, show how the auxiliary domain dsRBD2 in DExH RNA helicase.

The pattern matching swiss knife. Contribute to VirusTotal/yara development by creating an account on GitHub.

2024/04/15 · Excessive production of reactive oxygen species (ROS) decreased the expression of the IFN-stimulated gene Dhx58 in hepatocytes and promoted ...